SARS-CoV-2 nucleocapsid protein adheres to replication organelles before viral assembly at the Golgi/ERGIC and lysosome-mediated egress

• DOI: 10.1126/sciadv.abl4895
• Publication Date: 2022-01-07T18:56:41Z
• Authors: Katharina M. Scherer; Luca Mascheroni; George W. Carnell; Lucia C. S. Wunde...; Stanislaw Makarchuk; Marius Brockhoff; Ioanna Mela; Ana Fernandez-Vil...; Max Barysevich; Hazel Stewart; Maria Suau Sans; Charlotte L. George; Jacob R. Lamb; Gabriele S. Kamin...; Jonathan L. Heeney; Clemens F. Kaminski
• Keywords: 0301 basic medicine; 0303 health sciences; Coronaviruses; FOS: Health sciences; 3101 Biochemistry and Cell Biology; 3. Good health; 3102 Bioinformatics and Computational Biology; 03 medical and health sciences; Coronaviruses Therapeutics and Interventions; Infectious Diseases; Emerging Infectious Diseases; 2.2 Factors relating to the physical environment; Biomedicine and Life Sciences; Infection; 31 Biological Sciences

Super-resolution optical imaging reveals the accumulation of SARS-CoV-2 nucleocapsid protein at viral replication organelles.