The Genome of the Sea Urchin Strongylocentrotus purpuratus

• DOI: 10.1126/science.1133609
• Publication Date: 2006-11-09T21:53:26Z
• Authors: Erica Sodergren; George M. Weinstock; Eric H Davidson; R. Andrew Cameron; Richard A. Gibbs; Robert C. Angerer; Lynne M. Angerer; Maria Ina Arnone; David R. Burgess; Robert D. Burke; James A. Coffman; Michael Dean; Maurice R. Elphick; Charles A. Ettensohn; Kathy R. Foltz; Amro Hamdoun; Richard O. Hynes; William H. Klein; William Marzluff; David R. McClay; Robert L. Morris; Arcady Mushegian; Jonathan P. Rast; L. Courtney Smith; Michael C. Thorndyke; Victor D. Vacquier; Gary M. Wessel; Greg Wray; Lan Zhang; Christine G. Elsik; Olga Ermolaeva; Wratko Hlavina; Gretchen Hofmann; Paul Kitts; Melissa J. Landrum; Aaron J. Mackey; Donna Maglott; Georgia Panopoulou; Albert J. Poustka; Kim Pruitt; Victor Sapojnikov; Xingzhi Song; Alexandre Souvorov; Victor Solovyev; Zheng Wei; Charles A. Whittaker; Kim Worley; K. James Durbin; Yufeng Shen; Olivier Fedrigo; David Garfield; Ralph Haygood; Alexander Primus; Rahul Satija; Tonya Severson; Manuel L. Gonzale...; Andrew R. Jackson; Aleksandar Milosa...; Mark Tong; Christopher E. Ki...; Brian T. Livingston; Fred H. Wilt; Nikki Adams; Robert Bellé; Seth Carbonneau; Rocky Cheung; Patrick Cormier; Bertrand Cosson; Jenifer Croce; Antonio Fernandez...; Anne-Marie Genevi...; Manisha Goel; Hemant Kelkar; Julia Morales; Odile Mulner-Lori...; Anthony J. Robertson; Jared V. Goldstone; Bryan Cole; David Epel; Bert Gold; Mark E. Hahn; Meredith Howard-A...; Mark Scally; John J. Stegeman; Erin L. Allgood; Jonah Cool; Kyle M. Judkins; Shawn S. McCafferty; Ashlan M. Musante; Robert A. Obar; Amanda P. Rawson; Blair J. Rossetti; Ian R. Gibbons; Matthew P. Hoffman; Andrew Leone; Sorin Istrail; Stefan C. Materna; Manoj P. Samanta; Viktor Stolc; Waraporn Tongprasit; Qiang Tu; Karl-Frederik Ber...; Bruce P. Brandhorst; James Whittle; Kevin Berney; David J. Bottjer; Cristina Calestani; Kevin Peterson; Elly Chow; Qiu Autumn Yuan; Eran Elhaik; Dan Graur; Justin T. Reese; Ian Bosdet; Shin Heesun; Marco A. Marra; Jacqueline Schein; Michele K. Anderson; Virginia Brockton; Katherine M. Buckley; Avis H. Cohen; Sebastian D. Fugmann; Taku Hibino; Mariano Loza-Coll; Audrey J. Majeske; Cynthia Messier; Sham V. Nair; Zeev Pancer; David P. Terwilliger; Cavit Agca; Enrique Arboleda; Nansheng Chen; Allison M. Churcher; F. Hallböök; Glen W. Humphrey; Mohammed M. Idris; Takae Kiyama; Shuguang Liang; Dan Mellott; Xiuqian Mu; Greg Murray; Robert P. Olinski; Florian Raible; Matthew Rowe; John S. Taylor; Kristin Tessmar-R...; D. Wang; Karen H. Wilson; Shunsuke Yaguchi; Terry Gaasterland; Blanca E. Galindo; Herath J. Gunaratne; Celina Juliano; Masashi Kinukawa; Gary W. Moy; Anna T. Neill; Mamoru Nomura; Michael Raisch; Anna Reade; Michelle M. Roux; Jia L. Song; Yi-Hsien Su; Ian K. Townley; Ekaterina Voronina; Julian L. Wong; Gabriele Amore; Margherita Branno; Euan R. Brown; Vincenzo Cavalieri; Véronique Duboc; Louise Duloquin; Constantin Flytzanis; Christian Gache; François Lapraz; Thierry Lepage; Annamaria Locascio; Pedro Martinez; Giorgio Matassi; Valeria Matranga; Ryan Range; Francesca Rizzo; Eric Röttinger; Wendy Beane; Cynthia Bradham; Christine Byrum; Tom Glenn; Sofia Hussain; Gerard Manning; Esther Miranda; Rebecca Thomason; Katherine Walton; Athula Wikramanayke; Shu-Yu Wu; Ronghui Xu; C. Titus Brown; Lili Chen; Rachel F. Gray; Pei Yun Lee; Jongmin Nam; Paola Oliveri; Joel Smith; Donna Muzny; Stephanie Bell; Joseph Chacko; Andrew Cree; Stacey Curry; Clay Davis; Huyen Dinh; Shannon Dugan-Rocha; Jerry Fowler; Rachel Gill; Cerrissa Hamilton; Judith Hernandez; Sandra Hines; Jennifer Hume; LaRonda Jackson; Angela Jolivet; Christie Kovar; Sandra Lee; Lora Lewis; George Miner; Margaret Morgan; Lynne V. Nazareth; Geoffrey Okwuonu; David Parker; Ling-Ling Pu; Rachel Thorn; Rita Wright
• Keywords: Strongylocentrotus purpuratus; Echinoderm; Deuterostome; Chordate

We report the sequence and analysis of 814-megabase genome sea urchin Strongylocentrotus purpuratus , a model for developmental systems biology. The sequencing strategy combined whole-genome shotgun bacterial artificial chromosome (BAC) sequences. This use BAC clones, aided by pooling strategy, overcame difficulties associated with high heterozygosity genome. encodes about 23,300 genes, including many previously thought to be vertebrate innovations or known only outside deuterostomes. echinoderm provides an evolutionary outgroup chordates yields insights into evolution