The Ecoresponsive Genome of Daphnia pulex

• DOI: 10.1126/science.1197761
• Publication Date: 2011-02-03T19:31:16Z
• Authors: John K. Colbourne; Michael E. Pfrender; Donald Gilbert; W. Kelley Thomas; Abraham Tucker; Todd H. Oakley; Shinichi Tokishita; Andrea Aerts; Georg J. Arnold; Malay Kumar Basu; Darren J. Bauer; Carla E. Cáceres; Liran Carmel; Claudio Casola; Jeong-Hyeon Choi; John C. Detter; Qunfeng Dong; Serge Dusheyko; Brian D. Eads; Thomas Fröhlich; Kerry A. Geiler-S...; Daniel Gerlach; Phil Hatcher; Sanjuro Jogdeo; Jeroen Krijgsveld; Evgenia V. Kriven...; Dietmar Kültz; Christian Laforsch; Erika Lindquist; Jacqueline Lopez; J. Robert Manak; Jean Muller; Jasmyn Pangilinan; Rupali P. Patwardhan; Samuel Pitluck; Ellen J. Pritham; Andreas Rechtsteiner; Mina Rho; Igor B. Rogozin; Onur Sakarya; Asaf Salamov; Sarah Schaack; Harris Shapiro; Yasuhiro Shiga; Courtney Skalitzky; Zachary Smith; Alexander Souvorov; Way Sung; Zuojian Tang; Dai Tsuchiya; Hank Tu; Harmjan Vos; Mei Wang; Yuri I. Wolf; Hideo Yamagata; Takuji Yamada; Yuzhen Ye; Joseph R. Shaw; Justen Andrews; Teresa J. Crease; Haixu Tang; Susan M. Lucas; Hugh M. Robertson; Peer Bork; Eugene V. Koonin; Evgeny M. Zdobnov; Igor V. Grigoriev; Michael Lynch; Jeffrey L. Boore
• Keywords: Daphnia pulex; Multitude

We describe the draft genome of microcrustacean Daphnia pulex, which is only 200 megabases and contains at least 30,907 genes. The high gene count a consequence an elevated rate duplication resulting in tandem clusters. More than third Daphnia's genes have no detectable homologs any other available proteome, most amplified families are specific to lineage. coexpansion interacting within metabolic pathways suggests that maintenance duplicated not random, analysis expression under different environmental conditions reveals numerous paralogs acquire divergent patterns soon after duplication. Daphnia-specific genes, including many additional loci sequenced regions otherwise devoid annotations, responsive ecological challenges.