The Genetic Landscape of the Childhood Cancer Medulloblastoma

• DOI: 10.1126/science.1198056
• Publication Date: 2010-12-17T03:55:51Z
• Authors: D. Williams Parsons; Meng Li; Xiaosong Zhang; Siân Jones; Rebecca J. Leary; Jimmy Cheng-Ho Lin; Simina M. Boca; Hannah Carter; Josue Samayoa; Chetan Bettegowda; Gary L. Gallia; George I. Jallo; Zev A. Binder; Yuri Nikolsky; James Hartigan; Doug R. Smith; Daniela S. Gerhard; Daniel W. Fults; Scott VandenBerg; Mitchel S. Berger; Suely Kazue Nagah...; Sueli Mieko Oba S...; Carlos Clara; Peter C. Phillips; Jane E. Minturn; Jaclyn A. Biegel; Alexander R. Judkins; Adam C. Resnick; Phillip B. Storm; Tom Curran; Yiping He; B. Ahmed Rasheed; Henry S. Friedman; Stephen T. Keir; Roger McLendon; Paul A. Northcott; Michael D. Taylor; Peter C. Burger; Gregory J. Riggins; Rachel Karchin; Giovanni Parmigiani; Darell D. Bigner; Hai Yan; Nick Papadopoulos; Bert Vogelstein; Kenneth W. Kinzler; Victor E. Velculescu
• Keywords: Childhood Cancer

Genomic analysis of a childhood cancer reveals markedly fewer mutations than what is typically seen in adult cancers.