SAICAR Stimulates Pyruvate Kinase Isoform M2 and Promotes Cancer Cell Survival in Glucose-Limited Conditions
0301 basic medicine
Cell Survival
Pyruvate Kinase
Fibroblasts
Aminoimidazole Carboxamide
Recombinant Proteins
3. Good health
03 medical and health sciences
Glucose
Allosteric Regulation
Neoplasms
Tumor Microenvironment
Humans
Ribonucleosides
HeLa Cells
DOI:
10.1126/science.1224409
Publication Date:
2012-10-20T00:50:06Z
AUTHORS (3)
ABSTRACT
A metabolite is identified that may help cancer cells coordinate their mode of energy generation with nutrient conditions.
SUPPLEMENTAL MATERIAL
Coming soon ....
REFERENCES (24)
CITATIONS (191)
EXTERNAL LINKS
PlumX Metrics
RECOMMENDATIONS
FAIR ASSESSMENT
Coming soon ....
JUPYTER LAB
Coming soon ....