Stepwise Evolution of Essential Centromere Function in a Drosophila Neogene
Evolution, Molecular
0303 health sciences
03 medical and health sciences
Chromosomal Proteins, Non-Histone
Gene Duplication
Centromere
Molecular Sequence Data
Animals
Drosophila Proteins
Drosophila
Genes, Insect
Amino Acid Sequence
DOI:
10.1126/science.1234393
Publication Date:
2013-06-06T18:13:33Z
AUTHORS (9)
ABSTRACT
Essential Novelty
The evolution of essential function for newly originated genes presents a conundrum, in that prior to the gene's origin either the essential function was absent or else performed by another gene or set of genes. In order to better understand how new genes acquire essential function,
Ross
et al.
(p.
1211
) investigated the origin of the
Drosophila
gene
Umbrea. Umbrea
became an essential protein in certain
Drosophila
species through the gain of localization at the centromere and a role in chromosome segregation.
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