A Chloroplast Retrograde Signal Regulates Nuclear Alternative Splicing

• DOI: 10.1126/science.1250322
• Publication Date: 2014-04-11T06:18:16Z
• Authors: Ezequiel Petrillo; Micaela A. Godoy ...; Armin Fuchs; Dominik Reifer; John Fuller; Marcelo J. Yanovsky; Craig Simpson; John W. S. Brown; Andrea Barta; Maria Kalyna; Alberto R. Kornbl...
• Keywords: 0301 basic medicine; 570; Chloroplasts; Light; Plastoquinone; Seedling; RNA Stability; Messenger; Arabidopsis; Luz/Oscuridad; Genetically Modified; Models, Biological; Plant Roots; Plantas; Electron Transport; 03 medical and health sciences; Cloroplasto; Models; Gene Expression Regulation, Plant; https://purl.org/becyt/ford/1.6; Circadian Clocks; RNA, Messenger; Photosynthesis; https://purl.org/becyt/ford/1; 580; Cell Nucleus; Arabidopsis Proteins; Plant; Plants; Biological; Plants, Genetically Modified; Plant Leaves; Alternative Splicing; Dibromothymoquinone; Gene Expression Regulation; Diuron; RNA; Splicing Alternativo; Oxidation-Reduction; Signal Transduction

No Light Control

Light is the main source of energy for plants and is also used as a signal for growth and development: Indeed, it can modulate up to a fifth of the entire transcriptome in both Arabidopsis thaliana and rice.

Petrillo et al.

(p. 427 , published online 10 April) show that light can affect gene expression through alternative splicing of the serine-arginine rich protein At-RS31 , required for proper plant growth. But photoreceptors are not involved; rather, a mobile retrograde signal from the chloroplast controls the alternative splicing of At-RS31.