Molecular Genetics of the Bithorax Complex in Drosophila melanogaster

• DOI: 10.1126/science.221.4605.23
• Publication Date: 2006-10-05T18:37:18Z
• Authors: Welcome Bender; Michael Akam; François Karch; Philip A. Beachy; Mark Peifer; Pierre Spierer; E. B. Lewis; David S. Hogness
• Keywords: info:eu-repo/classification/ddc/570; 0301 basic medicine; 570; 03 medical and health sciences; ddc:570; 590

The bithorax complex in Drosophila melanogaster is a cluster of homeotic genes that specify developmental pathways for many the body segments fly. DNA has been isolated, and region 195,000 base pairs covers left half described here. lesions associated with mutants have identified, most are due to rearrangements. Most spontaneous insertions particular mobile element named "gypsy." This affects functions sequences removed from site insertion. Mutant given phenotypic class distributed over large distances up 73,000 pairs.