Myosin Phosphorylation and the Cross-Bridge Cycle in Arterial Smooth Muscle

• DOI: 10.1126/science.6893872
• Publication Date: 2006-10-05T13:45:58Z
• Authors: Patrick F. Dillon; Mark O. Aksoy; Steven P. Driska; Richard A. Murphy
• Keywords: Dephosphorylation; Bridge (graph theory)

Phosphorylation of the 20,000-dalton light chain myosin is closely correlated with cross-bridge cycling in arterial smooth muscle. Evidence presented that dephosphorylation can produce an attached, noncycling (latch-bridge) which responsible for high economy force maintenance this tissue.