Suprachiasmatic Stimulation Phase Shifts Rodent Circadian Rhythms

• DOI: 10.1126/science.7063851
• Publication Date: 2006-10-05T18:30:32Z
• Authors: Benjamin Rusak; Gerard Groos
• Keywords: Phase response curve; Chronobiology

The integrity of the suprachiasmatic nuclei (SCN) hypothalamus is essential to expression normal circadian rhythms in rodents. Electrical stimulation SCN caused phase shifts and period changes freerunning feeding rats activity hamsters. response curve for appears parallel that light pulses. These findings strengthen hypothesis derived from lesion studies are dominant light-entrained oscillators rodent system.