Microfluidic-like fabrication of metal ion–cured bioadhesives by mussels
0301 basic medicine
Mytilus edulis
Iron
Secretory Vesicles
Microfluidics
Proteins
Biological Transport
Vanadium
Spectrum Analysis, Raman
Dihydroxyphenylalanine
03 medical and health sciences
Adhesives
Animals
DOI:
10.1126/science.abi9702
Publication Date:
2021-10-16T02:02:59Z
AUTHORS (9)
ABSTRACT
Mussel mooring made mighty by metals
Mussels produce an exceptional proteinaceous adhesive so they can withstand waves and currents. Metal ions bound to modified tyrosine residues play an important role in reinforcing the adhesive. Priemel
et al
. brought together a variety of spectroscopy and microscopy techniques to study the cellular mechanisms involved in adhesive fabrication in mussels (see the Perspective by Wilker). They found that metal ion–rich vesicles are secreted alongside vesicles containing the adhesive protein and mix in a microfluidic-like process within interconnected microchannels found in the lateral duct of the mussel foot to create porous, adhesive plaque filaments. —MAF
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