Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity

• DOI: 10.1126/science.adl6173
• Publication Date: 2024-07-11T17:59:53Z
• Authors: Meng-Ju Wu; Hiroshi Kondo; Ashwin V. Kammula; Lei Shi; Yi Xiao; Sofiene Dhiab; Qin Xu; Chloe J Slater; Omar I. Avila; Joshua Merritt; Hiroyuki Kato; Prabhat Kattel; Jonathan Sussman; Ilaria Gritti; Jason Eccleston; Yi Sun; Hyo Min Cho; Kira Olander; Takeshi Katsuda; Diana D. Shi; Milan R. Savani; Bailey C. Smith; James M Cleary; Raul Mostoslavsky; Vindhya Vijay; Yosuke Kitagawa; Hiroaki Wakimoto; Russell W. Jenkins; Kathleen B. Yates; Jihye Paik; Ania Tassinari; Duygu Hatice Saat...; Adriana E. Tron; Wilhelm Haas; Daniel Cahill; Samuel K. McBrayer; Robert T. Manguso; Nabeel Bardeesy
• Keywords: DNA demethylation; TLR3; Isocitrate dehydrogenase

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