Peripheral lymph nodes contain migratory and resident innate lymphoid cell populations

• DOI: 10.1126/sciimmunol.aau8082
• Publication Date: 2019-05-31T23:15:11Z
• Authors: Emma E. Dutton; Dominika W. Gajdasik; Claire Willis; Remi Fiancette; Emma L. Bishop; Ana Camelo; Matthew A. Sleeman; Margherita Coccia; Arnaud M. Didierl...; Michio Tomura; Fernanda Pilataxi; Christopher A. Mo...; Gianluca Carlesso; David R. Withers
• Keywords: 0301 basic medicine; Receptors, CCR7; Mice, Transgenic; Inbred C57BL; L-Selectin/metabolism; Transgenic; Sphingosine-1-Phosphate Receptors/genetics; Innate/immunology; CCR7/metabolism; Interferon-gamma; Mice; 03 medical and health sciences; 0302 clinical medicine; Cell Movement; Receptors; Killer Cells; Lymph Nodes/cytology/immunology; Animals; Th1 Cells/immunology; L-Selectin; 10. No inequality; Sphingosine-1-Phosphate Receptors; Interferon-gamma/metabolism; Immunity; Th1 Cells; Flow Cytometry; Immunity, Innate; 3. Good health; Killer Cells, Natural; Mice, Inbred C57BL; Natural/immunology; Cell Movement/immunology; Lymph Nodes; Transcriptome

Innate lymphoid cells recirculate through peripheral lymph nodes and contribute to early IFN-γ production after immunization.