A discrete subset of epigenetically primed human NK cells mediates antigen-specific immune responses

• DOI: 10.1126/sciimmunol.aba6232
• Publication Date: 2020-10-16T23:11:08Z
• Authors: Victoria Stary; Ram Vinay Pandey; Johanna Strobl; Lisa Kleissl; Patrick Starlinger; David Pereyra; Wolfgang Weninger; Gottfried F. Fischer; Christoph Bock; Matthias Farlik; Georg Stary
• Keywords: Adult; Aged, 80 and over; Male; Biopsy; Integrin alpha1; Cell Separation; Adaptive Immunity; Middle Aged; Patch Tests; Dermatitis, Contact; Flow Cytometry; Lymphocyte Subsets; Epigenesis, Genetic; 3. Good health; Killer Cells, Natural; 03 medical and health sciences; 0302 clinical medicine; Liver; Nickel; Cell Line, Tumor; Humans; Female; Aged

CD49a + CD16 − NK cells from the liver and contact dermatitis lesions specifically recognize antigens and contribute to adaptive immunity.