Human γδ T cell sensing of AMPK-dependent metabolic tumor reprogramming through TCR recognition of EphA2

• DOI: 10.1126/sciimmunol.aba9010
• Publication Date: 2021-07-30T19:42:04Z
• Authors: Christelle Harly; Stephen Paul Joyce; Charlotte Domblides; Thomas Bachelet; Vincent Pitard; Charlotte Mannat; Angela Pappalardo; Lionel Couzi; Sonia Netzer; Layal Massara; Emilie Obre; Omar Hawchar; Lydia Lartigue; Stéphane Claverol; Carla Cano; Jean-François Moreau; Isabelle Mahouche; Isabelle Soubeyran; Rodrigue Rossignol; Benoit Viollet; Carrie R. Willcox; Fiyaz Mohammed; Benjamin E. Willcox; Benjamin Faustin; Julie Déchanet-Me...
• Keywords: Mice, Knockout; 0303 health sciences; Receptor, EphA2; Antibodies, Monoclonal; [SDV.CAN]Life Sciences [q-bio]/Cancer; Receptors, Antigen, T-Cell, gamma-delta; AMP-Activated Protein Kinases; Cell Line; 3. Good health; Mice; 03 medical and health sciences; Neoplasms; Animals; Humans; Antigens; Intraepithelial Lymphocytes

A γδ TCR senses metabolic tumor reprogramming through recognition of EphA2.