Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation

• DOI: 10.1126/sciimmunol.abb7221
• Publication Date: 2021-02-26T20:06:54Z
• Authors: Daniel F. Dwyer; Jose Ordovas-Mont...; Samuel J. Allon; Kathleen M. Buchheit; Marko Vukovic; Tahereh Derakhshan; Chunli Feng; Juying Lai; Travis K. Hughes; Sarah K. Nyquist; Matthew P. Giannetti; Bonnie Berger; Neil Bhattacharyya; Rachel E. Roditi; Howard R. Katz; Martijn C. Nawijn; Marijn Berg; Maarten van den B...; Tanya M. Laidlaw; Alex K. Shalek; Nora A. Barrett; Joshua A. Boyce
• Keywords: Allergic Inflammation; Mast (botany)

Mast cells in type 2 airway inflammation exhibit heterogeneous inflammation-associated phenotypes and proliferate situ.