Inhibition of mTOR Signaling in Parkinson’s Disease Prevents l -DOPA–Induced Dyskinesia

• DOI: 10.1126/scisignal.2000308
• Publication Date: 2009-09-24T00:22:44Z
• Authors: Emanuela Santini; Myriam Heiman; Paul Greengard; Emmanuel Valjent; Gilberto Fisone
• Keywords: Medium spiny neuron

Dyskinetic side effects of a Parkinson’s disease medication may involve dopamine D1 receptor–mediated activation mTORC1.