SH3 Domain–Based Phototrapping in Living Cells Reveals Rho Family GAP Signaling Complexes

• DOI: 10.1126/scisignal.2002189
• Publication Date: 2011-12-01T04:44:26Z
• Authors: Hirokazu Okada; Akiyoshi Uezu; Frank M. Mason; Erik J. Soderblom; M. Arthur Moseley; Scott H. Soderling
• Keywords: Proteomics; src Homology Domains; 0303 health sciences; 03 medical and health sciences; HEK293 Cells; GTPase-Activating Proteins; Humans; Receptors, GABA-A; Models, Biological; Signal Transduction

Domain-based proteomics analysis identifies binding partners and potential functions for a family of GTPase-activating proteins that regulate the cytoskeleton.