Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia

• DOI: 10.1126/scisignal.2005500
• Publication Date: 2014-11-18T20:33:28Z
• Authors: Viraj R. Sanghvi; Konstantinos J. M...; Joni Van der Meulen; Michael Boice; Andrew L. Wolfe; Mark Carty; Prathibha Mohan; Pieter Rondou; Nicholas D. Socci; Yves Benoit; Tom Taghon; Pieter Van Vlierb...; Christina S. Leslie; Frank Speleman; Hans-Guido Wendel
• Keywords: 0301 basic medicine; Models, Genetic; Genes, myb; Reverse Transcriptase Polymerase Chain Reaction; Hematopoietic Stem Cell Transplantation; High Mobility Group Proteins; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma; Adoptive Transfer; Gene Expression Regulation, Neoplastic; Repressor Proteins; Mice; MicroRNAs; 03 medical and health sciences; Artificial Intelligence; T-Lymphocyte Subsets; Animals; Humans; Genes, Tumor Suppressor

A set of microRNAs that target the Myb oncogene may function as tumor suppressors in T cell leukemia.