Cholesterol modulates Orai1 channel function

• DOI: 10.1126/scisignal.aad7808
• Publication Date: 2016-01-26T19:43:17Z
• Authors: Isabella Derler; Isaac Jardin; Peter B. Stathopulos; Martin Muik; Marc Fahrner; Vasilina Zayats; Saurabh K. Pandey; Michael Poteser; Barbara Lackner; Marketa Absolonova; Rainer Schindl; Klaus Groschner; Rüdiger Ettrich; Mitsu Ikura; Christoph Romanin
• Keywords: Orai1; Calcium in biology

Cholesterol suppresses the activity of a channel needed to refill intracellular calcium stores.