Reduced abundance of the E3 ubiquitin ligase E6AP contributes to decreased expression of the INK4/ARF locus in non–small cell lung cancer

Mice, Knockout 0301 basic medicine Lung Neoplasms Nuclear Proteins Cell Cycle Proteins Kaplan-Meier Estimate DNA Methylation Fibroblasts Embryo, Mammalian 3. Good health Gene Expression Regulation, Neoplastic 03 medical and health sciences Carcinoma, Non-Small-Cell Lung Cell Line, Tumor Animals Humans Cyclin-Dependent Kinase Inhibitor p19 Promoter Regions, Genetic Cells, Cultured Cyclin-Dependent Kinase Inhibitor p16 E2F1 Transcription Factor Cyclin-Dependent Kinase Inhibitor p15 Protein Binding
DOI: 10.1126/scisignal.aaf8223 Publication Date: 2017-01-10T19:30:24Z