Inhibition of somatosensory mechanotransduction by annexin A6

Male 0301 basic medicine 570 Cell biology 1303 Biochemistry Sensory Receptor Cells Molecular biology 610 Pain Biochemistry Mechanotransduction, Cellular Ion Channels 1307 Cell Biology Mice 03 medical and health sciences Osteoarthritis 1312 Molecular Biology Animals Biotinylation [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC] Annexin A6 Cells, Cultured Mice, Knockout Arthritis, Experimental Peptide Fragments Mice, Inbred C57BL [SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology Conotoxins
DOI: 10.1126/scisignal.aao2060 Publication Date: 2018-06-19T18:15:35Z
ABSTRACT
The membrane-binding protein annexin A6 suppresses mechanically induced pain in a mouse model of osteoarthritis.
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