A Generalized Linear-Quadratic Model for Radiosurgery, Stereotactic Body Radiation Therapy, and High–Dose Rate Brachytherapy

• DOI: 10.1126/scitranslmed.3000864
• Publication Date: 2010-07-07T22:18:49Z
• Authors: Jian Z. Wang; Zhibin Huang; Simon S. Lo; William T. C. Yuh; Nina A. Mayr
• Keywords: Mice; 03 medical and health sciences; 0302 clinical medicine; Brachytherapy; Linear Models; Animals; Dose-Response Relationship, Radiation; Pneumonia; Radiosurgery; 3. Good health

A generalized mathematical model for the relation between radiation dose and tumor cell death enables better treatment planning and dose schedule designs for current targeted high-dose radiation therapies in cancer.