Dynamics of Dengue Disease Severity Determined by the Interplay Between Viral Genetics and Serotype-Specific Immunity

• DOI: 10.1126/scitranslmed.3003084
• Publication Date: 2011-12-21T20:19:26Z
• Authors: Molly OhAinle; Angel Balmaseda; Alexander R. Maca...; Yolanda Tellez; Michael C. Zody; Saira Saborío; Andrea Nuñez; Niall J. Lennon; Bruce W. Birren; Aubree Gordon; Matthew R. Henn; Eva Harris
• Keywords: Dengue; 0301 basic medicine; 03 medical and health sciences; Molecular Sequence Data; Humans; Dengue Virus; Severity of Illness Index; 3. Good health

The complex interactions between serotype-specific immunity and viral genetics drive dengue disease outcomes in endemic populations.