Synthetic Generation of Influenza Vaccine Viruses for Rapid Response to Pandemics

• DOI: 10.1126/scitranslmed.3006368
• Publication Date: 2013-05-15T18:42:27Z
• Authors: Philip R. Dormitzer; Pirada Suphaphiphat; Daniel G. Gibson; David E. Wentworth; Timothy B. Stockwell; Mikkel A. Algire; Nina Alperovich; Mario Barro; David M. Brown; Stewart Craig; Brian M. Dattilo; Evgeniya A. Denisova; Ivna De Souza; Markus Eickmann; Vivien G. Dugan; Annette Ferrari; Raul C. Gomila; Liqun Han; Casey Judge; Sarthak Mane; Mikhail Matrosovich; Chuck Merryman; Giuseppe Palladino; Gene A. Palmer; Terika Spencer; Thomas Strecker; Heidi Trusheim; Jennifer Uhlendorff; Yingxia Wen; Anthony C. Yee; Jayshree Zaveri; Bin Zhou; Stephan Becker; Armen Donabedian; Peter W. Mason; John I. Glass; Rino Rappuoli; J. Craig Venter
• Keywords: Pandemic; Neuraminidase inhibitor

Synthesis of viral genes from sequence information allows rapid generation influenza vaccine viruses, facilitating responses to pandemics.