Chitinase 3–Like 1 Suppresses Injury and Promotes Fibroproliferative Responses in Mammalian Lung Fibrosis

• DOI: 10.1126/scitranslmed.3007096
• Publication Date: 2014-06-12T04:49:54Z
• Authors: Yang Zhou; Hong Peng; Huanxing Sun; Xueyan Peng; Chuyan Tang; Ye Gan; Xiaosong Chen; Aditi Mathur; Buqu Hu; Martin D. Slade; Ruth R. Montgomery; Albert C. Shaw; Robert J. Homer; Eric S. White; Chang-Min Lee; Meagan W. Moore; Mridu Gulati; Chun Geun Lee; Jack A. Elias; Erica L. Herzog
• Keywords: Chitinase; Lung Fibrosis

Chitinase 3–like 1 protects against lung injury but has a profibrotic role during the repair phase.