Cell Distance Mapping Identifies Functional T Follicular Helper Cells in Inflamed Human Renal Tissue

• DOI: 10.1126/scitranslmed.3008146
• Publication Date: 2014-04-02T18:33:45Z
• Authors: Vladimir M. Liarski; Natalya Kaverina; Anthony Chang; Daniel Brandt; Denisse Yanez; Lauren Talasnik; Gianluca Carlesso; Ronald Herbst; Tammy O. Utset; Christine Labno; Yahui Peng; Yulei Jiang; Maryellen L. Giger; Marcus R. Clark
• Keywords: Inflammation; 0301 basic medicine; B-Lymphocytes; Interleukins; Computational Biology; Cell Communication; T-Lymphocytes, Helper-Inducer; Kidney; Lupus Nephritis; 03 medical and health sciences; Imaging, Three-Dimensional; Proto-Oncogene Proteins c-bcl-6; Humans

Visualizing and quantifying the spatial relationships between T and B cells identifies adaptive immune cell networks in human inflammation.