Phenotypic assays identify azoramide as a small-molecule modulator of the unfolded protein response with antidiabetic activity

• DOI: 10.1126/scitranslmed.aaa9134
• Publication Date: 2015-06-17T18:39:58Z
• Authors: Suneng Fu; Abdullah Yalcin; Grace Y. Lee; Ping Li; Jason Fan; Ana Paula Arruda; Benedicte M. Pers; Mustafa Yilmaz; Kosei Eguchi; Gökhan S. Hotamis...
• Keywords: Folding (DSP implementation)

New assays that measure endoplasmic reticulum (ER) function and protein folding identify a small molecule, azoramide, exerts antidiabetic effects.