Mortality factor 4 like 1 protein mediates epithelial cell death in a mouse model of pneumonia

• DOI: 10.1126/scitranslmed.aac7793
• Publication Date: 2015-10-28T20:47:13Z
• Authors: Chunbin Zou; Jin Li; Sheng Xiong; Yan Chen; Qin Wu; Xiuying Li; Nathaniel M. Weat...; SeungHye Han; Courtney Snavely; Bill B. Chen; Rama K. Mallampalli
• Keywords: Male; 0301 basic medicine; Medical Biotechnology; Medical biotechnology; In Vitro Techniques; Inbred C57BL; Medical and Health Sciences; Mice; 03 medical and health sciences; Rare Diseases; 2.1 Biological and endogenous factors; Animals; Humans; Pseudomonas Infections; Aetiology; Lung; Biomedical and Clinical Sciences; Animal; Epithelial Cells; Pneumonia; Biological Sciences; Middle Aged; 3. Good health; Mice, Inbred C57BL; Disease Models, Animal; Infectious Diseases; Good Health and Well Being; Disease Models; Pseudomonas aeruginosa; Pneumonia & Influenza; Infection; Biomedical engineering; Transcription Factors

Antagonism of Morf4l1 protein reduces lung cytotoxicity in a mouse model of pneumonia.