Complement C3 deficiency protects against neurodegeneration in aged plaque-rich APP/PS1 mice

• DOI: 10.1126/scitranslmed.aaf6295
• Publication Date: 2017-08-17T17:23:34Z
• Authors: Qiaoqiao Shi; Saba Chowdhury; Rong Ma; Kevin X. Le; Soyon Hong; Barbara J. Caldarone; Beth Stevens; Cynthia A. Lemere
• Keywords: Complement

C3 deficiency protects against hippocampal neurodegeneration and cognitive decline in aged APP/PS1 mice despite abundant Aβ plaques.