Cardiac repair in guinea pigs with human engineered heart tissue from induced pluripotent stem cells

• DOI: 10.1126/scitranslmed.aaf8781
• Publication Date: 2016-11-02T18:15:50Z
• Authors: Florian Weinberger; Kaja Breckwoldt; Simon Pecha; Allen Kelly; Birgit Geertz; Jutta Starbatty; Timur Yorgan; Kai-Hung Cheng; Katrin Lessmann; Tomas Stolen; Marielle Scherrer...; Godfrey Smith; Hermann Reichensp...; Arne Hansen; Thomas Eschenhagen
• Keywords: 0303 health sciences; Tissue Engineering; Heart Ventricles; Myocardium; Guinea Pigs; Induced Pluripotent Stem Cells; Cell Differentiation; Heart; Cicatrix; 03 medical and health sciences; Echocardiography; Animals; Humans; Regeneration; Female; Myocytes, Cardiac; Cardiac Surgical Procedures; Lung; Spleen; Cell Proliferation

Human engineered heart tissue derived from induced pluripotent stem cells improves cardiac function in guinea pigs.