Combined immune checkpoint blockade as a therapeutic strategy for BRCA1 -mutated breast cancer

• DOI: 10.1126/scitranslmed.aal4922
• Publication Date: 2017-08-17T17:23:39Z
• Authors: Emma Nolan; Peter Savas; Antonia N. Policheni; Phillip K. Darcy; François Vaillant; Christopher P. Mi...; Sathana Dushyanthen; Mariam Mansour; Jia-Min B. Pang; Stephen B. Fox; ; Charles M. Perou; Jane E. Visvader; Daniel H. D. Gray; Sherene Loi; Geoffrey J. Lindeman
• Keywords: Immune checkpoint

BRCA1 -mutated tumors may be particularly vulnerable to dual checkpoint inhibition.