Glycolysis links reciprocal activation of myeloid cells and endothelial cells in the retinal angiogenic niche

• DOI: 10.1126/scitranslmed.aay1371
• Publication Date: 2020-08-05T23:30:12Z
• Authors: Zhiping Liu; Jiean Xu; Qian Ma; Xiaoyu Zhang; Qiuhua Yang; Lina Wang; Yapeng Cao; Zhimin Xu; Amany Tawfik; Ye Sun; Neal L. Weintraub; David J. Fulton; Mei Hong; Zheng Dong; Lois E. H. Smith; Ruth B. Caldwell; Akrit Sodhi; Yuqing Huo
• Keywords: Mice, Knockout; Mice; 0303 health sciences; 03 medical and health sciences; Phosphofructokinase-2; Macrophages; Animals; Endothelial Cells; Glycolysis

Increased glycolysis facilitates reciprocal activation between myeloid cells and endothelial cells in pathological retinal angiogenesis.