A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles

• DOI: 10.1126/scitranslmed.aay5445
• Publication Date: 2020-11-19T00:23:47Z
• Authors: Jan Claesen; Jennifer B. Spagnolo; Stephany Flores R...; Kenji L. Kurita; Allyson L. Byrd; Alexander A. Aksenov; Alexey V. Melnik; Weng R. Wong; Shuo Wang; Ryan D. Hernandez; Mohamed S. Donia; Pieter C. Dorrestein; Heidi H. Kong; Julia A. Segre; Roger G. Linington; Michael A. Fischbach; Katherine P. Lemon
• Keywords: 0303 health sciences; Biomedical and Clinical Sciences; Microbiota; Medical Biotechnology; Biomedical Engineering; Medical biotechnology; 610; 600; Biological Sciences; Medical and Health Sciences; Anti-Bacterial Agents; 3. Good health; 03 medical and health sciences; Engineering; Infectious Diseases; Genetics; 2.2 Factors relating to the physical environment; Humans; Microbiome; Propionibacterium acnes; Infection; Biomedical engineering; Hair Follicle; Skin

Cutimycin, a thiopeptide antibiotic produced by the skin commensal Cutibacterium acnes , reduces Staphylococcus colonization of human skin hair follicles.