Bacterial cytoplasmic membranes synergistically enhance the antitumor activity of autologous cancer vaccines

• DOI: 10.1126/scitranslmed.abc2816
• Publication Date: 2021-07-07T19:25:03Z
• Authors: Long Chen; Hao Qin; Ruifang Zhao; Xiao Zhao; Liangru Lin; Yang Chen; Yixuan Lin; Yao Li; Yuting Qin; Yiye Li; Shaoli Liu; Keman Cheng; Hanqing Chen; Jian Shi; Gregory J. Anderson; Yan Wu; Yuliang Zhao; Guangjun Nie
• Keywords: 0301 basic medicine; Cell Membrane; Melanoma, Experimental; Dendritic Cells; CD8-Positive T-Lymphocytes; Cancer Vaccines; 3. Good health; Mice, Inbred C57BL; Mice; 03 medical and health sciences; Adjuvants, Immunologic; Animals; Humans

A nanovaccine based on bacterial cytoplasmic membranes and cell membranes from resected tumor tissue prevents tumor recurrence in mice.