Antibody signature induced by SARS-CoV-2 spike protein immunogens in rabbits

• DOI: 10.1126/scitranslmed.abc3539
• Publication Date: 2020-06-08T23:05:46Z
• Authors: Supriya Ravichandran; Elizabeth M. Coyle; Laura Klenow; Juanjie Tang; Gabrielle Grubbs; Shufeng Liu; Tony Wang; Hana Golding; Surender Khurana
• Keywords: 0301 basic medicine; General Medicine; Antibodies, Viral; Antibodies, Neutralizing; 3. Good health; Epitopes; 03 medical and health sciences; Neutralization Tests; Antibody Formation; Spike Glycoprotein, Coronavirus; Animals; Female; Immunization; Rabbits; Antigens, Viral; Reports

Understanding antibody epitope diversity and affinity generated by SARS-CoV-2 spike antigens in rabbits can aid COVID-19 vaccine development.