Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia

• DOI: 10.1126/scitranslmed.abf0113
• Publication Date: 2021-09-08T19:02:14Z
• Authors: Deena Iskander; Guanlin Wang; Elisabeth F. Heuston; Chrysi Christodou...; Bethan Psaila; Kanagaraju Ponnusamy; Hongwei Ren; Zeinab Mokhtari; Mark Robinson; Aristeidis Chaidos; Pritesh Trivedi; Nikolaos Trasanidis; Alexia Katsarou; Richard Szydlo; Carmen G. Palii; Mehmood H. Zaidi; Qais Al-Oqaily; Valentina S. Caputo; Anindita Roy; Yvonne Harrington; Leena Karnik; Kikkeri Naresh; Adam J. Mead; Supat Thongjuea; Marjorie Brand; Josu de la Fuente; David M. Bodine; Irene Roberts; Anastasios Karadi...
• Keywords: Diamond–Blackfan anemia; Ineffective erythropoiesis

Genotype-phenotype correlations are revealed by bone marrow single-cell RNA sequencing in Diamond-Blackfan anemia.