Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe

• DOI: 10.1126/scitranslmed.adl4497
• Publication Date: 2024-05-15T17:58:51Z
• Authors: Vitor M. Pereira; Pedro Lylyk; Nicole Cancelliere; Pedro N. Lylyk; Ivan Lylyk; Vania Anagnostakou; Carlos Bleise; Hidehisa Nishi; Mark Epshtein; Robert M. King; Mohammed Salman S...; Ajit S. Puri; Conrad W. Liang; Ricardo A. Hanel; Julian Spears; Thomas R. Marotta; Demetrius K. Lopes; Matthew J. Gounis; Giovanni J. Ughi
• Keywords: Microscopy; Miniaturization; Endovascular Procedures; Neurosurgery; Cerebral Arteries; 03 medical and health sciences; 0302 clinical medicine; cerebral artery disease; endovascular interventions; Humans; nOCT; Tomography, Optical Coherence; miniaturized endovascular neuro optical coherence tomography

Endovascular interventions are increasingly becoming the preferred approach for treating strokes and cerebral artery diseases. These procedures rely on sophisticated angiographical imaging guidance, which encounters challenges because of limited contrast spatial resolution. Achieving a more precise visualization underlying arterial pathology neurovascular implants is crucial accurate procedural decision-making. In human study involving 32 patients, we introduced clinical application miniaturized endovascular neuro optical coherence tomography (