Population Pharmacokinetics and Cerebrospinal Fluid Penetration of Fluconazole in Adults with Cryptococcal Meningitis

• DOI: 10.1128/aac.00885-18
• Publication Date: 2018-06-13T09:50:40Z
• Authors: Katharine E. Stott; Justin Beardsley; Ruwanthi Kolamunn...; Anahi Santoyo Cas...; Freddie Mukasa Ki...; Nguyen Thi Hoang Mai; Nguyễn Lê Nhu’ Tùng; Ngo Thi Kim Cuc; Jeremy Day; William Hope
• Keywords: Cryptococcal meningitis; Population Pharmacokinetics

Robust population pharmacokinetic (PK) data for fluconazole are scarce. The variability of penetration into the central nervous system (CNS) is not known.