Expansion of Vancomycin-Resistant Enterococcus faecium in an Academic Tertiary Hospital in Southwest Germany: a Large-Scale Whole-Genome-Based Outbreak Investigation

• DOI: 10.1128/aac.01978-18
• Publication Date: 2019-02-20T12:52:46Z
• Authors: Jan Liese; Leonard Schüle; Philipp Oberhetti...; Leonie Tschörner; Tran Nguyen; Daniela Dörfel; Wichard Vogel; Matthias Marschal; Ingo Autenrieth; Matthias Willmann; Silke Peter
• Keywords: 0301 basic medicine; BACTEREMIA; hospital epidemiology; MORTALITY; Enterococcus faecium; Microbial Sensitivity Tests; Anti-Bacterial Agents; Vancomycin-Resistant Enterococci; 3. Good health; EMERGENCE; 03 medical and health sciences; vancomycin resistance; whole-genome sequencing; Vancomycin; Germany; transmission routes; Humans; Genome, Bacterial; CLONES; Multilocus Sequence Typing

Vancomycin-resistant Enterococcus faecium (VREfm) is a frequent cause of nosocomial outbreaks. In the second half of 2015, a sharp increase in the incidence of VREfm was observed at our university medical center.