Co-occurrence of Plasmid-Mediated Tigecycline and Carbapenem Resistance in Acinetobacter spp. from Waterfowls and Their Neighboring Environment

• DOI: 10.1128/aac.02502-19
• Publication Date: 2020-02-28T14:30:10Z
• Authors: Chao-Yue Cui; Chong Chen; Bao-Tao Liu; Qian He; Xiao-Ting Wu; Ruan-Yang Sun; Yan Zhang; Ze-Hua Cui; Wen-Ying Guo; Qiu-lin Jia; Cang Li; Barry N. Kreiswirth; Xiao-Ping Liao; Liang Chen; Ya-Hong Liu; Jian Sun
• Keywords: Tigecycline

Tigecycline serves as one of the antibiotics last resort to treat multidrug-resistant (including carbapenem-resistant) pathogens. However, recently emerged plasmid-mediated tigecycline resistance mechanism, Tet(X), challenges clinical efficacy this class antibiotics. In study, we detected 180