In vitro evaluation of the antimicrobial activity of lichen metabolites as potential preservatives

• DOI: 10.1128/aac.28.2.289
• Publication Date: 2012-06-28T00:04:52Z
• Authors: K Ingólfsdóttir; S F Bloomfield; P J Hylands
• Keywords: Active compound

Antimicrobial screening of several lichen species and subsequent isolation structure elucidation active compounds revealed that the hydrolysis products certain metabolites, i.e., depsides, were against gram-negative bacteria fungi as well gram-positive bacteria. The constituents isolated from Stereocaulon alpinum Peltigera aphthosa identified, respectively, methyl beta-orsellinate a mixture ethyl orsellinates. MIC determinations indicated activity these was superior to commonly used preservative agents propyl p-hydroxybenzoates same order chlorocresol.