Transcription Factor NsdD Regulates the Expression of Genes Involved in Plant Biomass-Degrading Enzymes, Conidiation, and Pigment Biosynthesis in Penicillium oxalicum
2. Zero hunger
0303 health sciences
Gene Expression Profiling
Penicillium
Pigments, Biological
Spores, Fungal
Gene Expression Regulation, Enzymologic
Fungal Proteins
03 medical and health sciences
Biodegradation, Environmental
Cellulase
Gene Expression Regulation, Fungal
Glucan 1,4-alpha-Glucosidase
alpha-Amylases
Cellulose
Polyketide Synthases
Transcription Factors
DOI:
10.1128/aem.01039-18
Publication Date:
2018-07-06T10:07:29Z
AUTHORS (8)
ABSTRACT
Most filamentous fungi produce a vast number of extracellular enzymes that are used commercially for biorefineries of plant biomass to produce biofuels and value-added chemicals, which might promote the transition to a more environmentally friendly economy. The expression of these extracellular enzyme genes is tightly controlled at the transcriptional level, which limits their yields. Hitherto our understanding of the regulation of expression of plant biomass-degrading enzyme genes in filamentous fungi has been rather limited. In the present study, regulatory roles of a key regulator, PoxNsdD, were further explored in the soil fungus
Penicillium oxalicum
, contributing to the understanding of gene regulation in filamentous fungi and revealing the biotechnological potential of
P
.
oxalicum
via genetic engineering.
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