Cyanochelins, an Overlooked Class of Widely Distributed Cyanobacterial Siderophores, Discovered by Silent Gene Cluster Awakening

• DOI: 10.1128/aem.03128-20
• Publication Date: 2021-06-16T14:56:44Z
• Authors: Tomáš Galica; Nicola Borbone; Jan Mareš; Andreja Kust; Alessia Caso; Germana Esposito; Kumar Saurav; Jan Hájek; Klára Řeháková; Petra Urajová; Valeria Costantino; Pavel Hrouzek
• Keywords: 0301 basic medicine; 2. Zero hunger; secondary metabolism; siderophores; Siderophores; Cyanobacteria; cyanobacteria; lipopeptides; Biosynthetic Pathways; Lipopeptides; 03 medical and health sciences; Bacterial Proteins; Multigene Family; Peptide Synthases; cyanobacteria, iron acquisition, lipopeptides, secondary metabolism, siderophores; Polyketide Synthases; Phylogeny; iron acquisition

All living organisms depend on iron as an essential cofactor for indispensable enzymes. However, the sources of bioavailable iron are often limited.