Characterization of a Novel Lytic Protein Encoded by the Bacillus cereus E33L Gene ampD as a Bacillus anthracis Antimicrobial Protein

0301 basic medicine Microscopy Microbial Viability Protein Stability Colony Count, Microbial N-Acetylmuramoyl-L-alanine Amidase 03 medical and health sciences Bacteriolysis Anti-Infective Agents Bacillus cereus Bacterial Proteins Bacillus anthracis Enzyme Stability
DOI: 10.1128/aem.06906-11 Publication Date: 2012-02-18T04:54:54Z
ABSTRACT
ABSTRACT Lytic proteins encoded by bacterial genomes have been implicated in cell wall biosynthesis and recycling. The Bacillus cereus E33L ampD gene encodes a putative N -acetylmuramoyl- l -alanine amidase. This gene, expressed in vitro , produced a very stable, highly active lytic protein. Very low concentrations rapidly and efficiently lyse vegetative Bacillus anthracis cells.
SUPPLEMENTAL MATERIAL
Coming soon ....
REFERENCES (19)
CITATIONS (7)