Ineffectiveness of Vi and chemically treated endotoxins as typhoid vaccines in mice challenged with a Salmonella typhosa-Salmonella typhimurium hybrid

• DOI: 10.1128/iai.12.6.1470-1471.1975
• Publication Date: 2020-01-03T01:47:33Z
• Authors: B B Diena; A Ryan; R Wallace; F E Ashton; E M Johnson; L S Baron
• Keywords: Salmonella enterica

Purified Vi antigen, acetic anthydride-treated Salmonella typhosa endotoxin, and potassium methylate-treated S. endotoxin employed as vaccines in Swiss white mice failed to protect these animals against challenge with a virulent typhimurium hybrid expressing antigens.