Complete Resequencing and Reannotation of the Lactobacillus plantarum WCFS1 Genome

• DOI: 10.1128/jb.06275-11
• Publication Date: 2011-12-07T21:26:38Z
• Authors: R. J. Siezen; C. Francke; B. Renckens; J. Boekhorst; M. Wels; M. Kleerebezem; S. A. F. T. van H...
• Keywords: lactic-acid bacteria; 0301 basic medicine; 0303 health sciences; mice; artemis; growth; Molecular Sequence Data; Molecular Sequence Annotation; Gene Expression Regulation, Bacterial; 3. Good health; 03 medical and health sciences; IGMD 3: Genomic disorders and inherited multi-system disorders; carbohydrate; identification; NCMLS 4: Energy and redox metabolism; gastrointestinal-tract; genes; fermentation; database; Genome, Bacterial; Lactobacillus plantarum

There is growing interest in the beneficial effects of Lactobacillus plantarum on human health. The genome L. WCFS1, first sequenced 2001, was resequenced using Solexa technology. We identified 116 nucleotide corrections and improved function prediction for nearly 1,200 proteins, with a focus metabolic functions cell surface-associated proteins.