STREPTOCOCCAL L FORMS V

• DOI: 10.1128/jb.84.6.1202-1208.1962
• Publication Date: 2020-01-03T21:24:14Z
• Authors: John Edwards; Charles Panos
• Keywords: Muramic acid; Coccus (insect)

Edwards, John (University of Illinois College Medicine, Chicago, and Albert Einstein Medical Center, Philadelphia, Pa.) Charles Panos . Streptococcal L-forms. V. Acid-soluble nucleotides a group A Streptococcus derived L form. J. Bacteriol. 84: 1202–1208. 1962.—This report deals with comparison the acid-soluble from A, type 12, β-hemolytic streptococcus stable This is first presence cell-wall precursor (uridine diphosphate-muramic acid-peptide) in Cells each organism were obtained during their logarithmic phases growth, harvested by centrifugation, washed osmotically protective NaCl solutions. The analytical procedures essentially those Franzen Binkley. Calculated values indicated that these results could not be accounted for dry-weight differences due to loss streptococcal cell wall. It was found both organisms contained same amount total nucleotide material. form no uridine monophosphate (UMP), large concentration diphosphate (UDP)-muramic acid-peptide, significant increase UDP- N -acetylglucosamine. similar containing muramic acid-peptide demonstrable parent coccus. Instead, UMP an unidentified resolved this region. Analyses extracts indicate probable two three originally isolated Park penicillin-treated Staphylococcus aureus UDP-muramic cultured continual absence penicillin points inability resynthesize rigid wall indicates synthetic mechanism has been permanently impaired.