A Canine Parvovirus Mutant Is Spreading in Italy

• DOI: 10.1128/jcm.42.3.1333-1336.2004
• Publication Date: 2004-03-05T23:57:55Z
• Authors: Vito Martella; Alessandra Cavalli; Annamaria Pratelli; Giancarlo Bozzo; Michele Camero; Domenico Buonavoglia; Donato Narcisi; Maria Tempesta; Canio Buonavoglia
• Keywords: 0301 basic medicine; Wolves; Geography; Parvovirus, Canine; Carnivora; Hemagglutination Inhibition Tests; 3. Good health; Parvoviridae Infections; Parvovirus; 03 medical and health sciences; Dogs; Italy; Mink; Animals; Dog Diseases; Antigens, Viral

ABSTRACT By antigenic and genetic characterization of canine parvovirus type 2 (CPV-2) strains collected in 2001 and 2002 in Italy, it was possible to observe the spread of viruses with an unusual mutation, Glu-426, affecting a major antigenic epitope of CPV-2. Out of 67 strains analyzed, 49 (73.13%) were characterized as CPV-2a, 6 (8.95%) were characterized as CPV-2b, and 12 (17.91%) were characterized as the Glu-426 mutant.