Five Genome Sequences of Subspecies B1 Human Adenoviruses Associated with Acute Respiratory Disease

• DOI: 10.1128/jvi.06593-11
• Publication Date: 2011-12-09T21:33:54Z
• Authors: Shoaleh Dehghan; Elizabeth B. Liu; Jason Seto; Sarah F. Torres; Nolan R. Hudson; Adriana E. Kajon; David Metzgar; David W. Dyer; James Chodosh; Morris S. Jones; Donald Seto
• Keywords: Strain (injury); Subspecies

ABSTRACT Five genomes of human subspecies B1 adenoviruses isolated from cases acute respiratory disease have been sequenced and archived for reference. These include representatives two prevalent genomic variants HAdV-7, i.e., HAdV-7h HAdV-7d2. The other three are HAdV-3/16, HAdV-16 strain E26, HAdV-3+7 Takeuchi. All recombinant genomes. Genomics bioinformatics provide detailed views into the genetic makeup these pathogens insight their molecular evolution. Retrospective characterization particularly problematic older such as (1987) intriguing isolates Takeuchi (1958) may clues to phenotypes serology suggest protocols prevention treatment.