Five Genome Sequences of Subspecies B1 Human Adenoviruses Associated with Acute Respiratory Disease
Adenovirus Infections, Human
0301 basic medicine
0303 health sciences
03 medical and health sciences
Base Sequence
Adenoviruses, Human
Acute Disease
Molecular Sequence Data
Humans
Genome, Viral
Respiratory Tract Infections
3. Good health
DOI:
10.1128/jvi.06593-11
Publication Date:
2011-12-09T21:33:54Z
AUTHORS (11)
ABSTRACT
ABSTRACT
Five genomes of human subspecies B1 adenoviruses isolated from cases of acute respiratory disease have been sequenced and archived for reference. These include representatives of two prevalent genomic variants of HAdV-7, i.e., HAdV-7h and HAdV-7d2. The other three are HAdV-3/16, HAdV-16 strain E26, and HAdV-3+7 strain Takeuchi. All are recombinant genomes. Genomics and bioinformatics provide detailed views into the genetic makeup of these pathogens and insight into their molecular evolution. Retrospective characterization of particularly problematic older pathogens such as HAdV-7h (1987) and intriguing isolates such as HAdV-3+7 strain Takeuchi (1958) may provide clues to their phenotypes and serology and may suggest protocols for prevention and treatment.
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CITATIONS (20)
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